top of page

What is chelate (key-late)

Updated: Jan 30, 2023

Minerals are key nutrients that your body requires to function. They affect various aspects of bodily function, such as growth, bone health, muscle contractions, fluid balance, and many other processes.


However, many are difficult for your body to absorb. That’s why chelated minerals, which are supplements touted for improved absorption, have gained interest recently.


Chelated minerals are bound to compounds like amino or organic acids, which are meant to boost your body’s uptake of the mineral at hand.


What are chelated minerals?

Minerals are a type of nutrient that your body needs to function properly. As your body cannot produce minerals, you must obtain them through your diet.

Yet, many are difficult to absorb. For example, your intestine may only absorb 0.4–2.5% of chromium from food (1Trusted Source).


Chelated minerals are meant to boost absorption. They’re bound to a chelating agent, which are typically organic compounds or amino acids that help prevent the minerals from interacting with other compounds.


For example, chromium picolinate is a type of chromium attached to three molecules of picolinic acid. It’s absorbed through a different pathway than dietary chromium and appears to be more stable in your body (2Trusted Source, 3Trusted Source).


Various types of chelated minerals

Most minerals are available in chelated form. Some of the most common include:

  • calcium

  • zinc

  • iron

  • copper

  • magnesium

  • potassium

  • cobalt

  • chromium

  • molybdenum


Do chelated minerals have better absorption?

Chelated minerals are often touted as having better absorption than non-chelated ones.

Several studies have compared the absorption of the two.


For example, a study in 15 adults found that chelated zinc (as zinc citrate and zinc gluconate) was absorbed around 11% more effectively than non-chelated zinc (as zinc oxide) (4Trusted Source).


Similarly, a study in 30 adults noted that magnesium glycerophosphate (chelated) raised blood magnesium levels significantly more than magnesium oxide (non-chelated) (5Trusted Source).


What’s more, some research suggests that taking chelated minerals may reduce the total amount you need to consume to reach healthy blood levels. This is important for people at risk of excess mineral intake, such as iron overload.


For example, in a study in 300 infants, giving 0.34 mg per pound of body weight (0.75 mg per kg) of iron bisglycinate (chelated) daily raised blood iron levels to levels similar to those caused by 4 times that amount of iron sulfate (non-chelated) (6Trusted Source).

Yet, not all studies give the same results.


A study in 23 postmenopausal women showed that 1,000 mg of calcium carbonate (non-chelated) was more rapidly absorbed and raised blood calcium levels more effectively than the same amount of calcium citrate (chelated) (7Trusted Source).


Meanwhile, a study in pregnant women with iron deficiency found no significant difference in blood iron levels when comparing chelated iron (ferrous bisglycinate) with regular iron (ferrous sulfate) (8Trusted Source).


In general, animal studies indicate that chelated minerals are absorbed more effectively (9Trusted Source, 10Trusted Source).


However, these findings should be interpreted with caution, as animals have significantly different digestive tracts than humans. These differences can affect mineral absorption.

Given that the current research is mixed, more research on chelated minerals is needed.


Should you buy chelated minerals?

In some situations, taking the chelated form of a mineral may be more suitable.

For instance, chelated minerals may benefit older adults. As you age, you may produce less stomach acid, which can affect mineral absorption (11Trusted Source).


Because chelated minerals are bound to an amino or organic acid, they don’t require as much stomach acid to be efficiently digested (12Trusted Source).


Similarly, people who experience stomach pain after taking supplements may benefit from chelated minerals, as they’re less dependent on stomach acid for digestion.

Nonetheless, regular, non-chelated minerals are sufficient for most adults.


Plus, chelated minerals tend to cost more than non-chelated ones. If cost is a concern for you, stick with regular mineral supplements.


Keep in mind that mineral supplements are unnecessary for most healthy adults unless your diet doesn’t provide enough to meet your daily needs. In most instances, mineral supplements aren’t a suitable replacement for dietary mineral intake.


Still, vegans, blood donors, pregnant women, and certain other populations may benefit from regularly supplementing with minerals.


If you plan on taking chelated minerals, you should speak with a healthcare professional beforehand.


The bottom line

Chelated minerals are those bound to a chelating agent, such as an organic or amino acid, to improve absorption.


Though they’re often said to be absorbed better than regular mineral supplements, the current research is mixed.


For certain populations, such as older adults and those with stomach issues, chelated minerals are a suitable alternative to regular minerals. However, for most healthy adults, there’s no need to choose one over the other.


How we reviewed this article:

May 20, 2020 Written By Ryan Raman

Edited By Christina Guzik

Medically Reviewed By Amy Richter, RD

Copy Edited By Christina Guzik, BA, MBA


4 views0 comments

Recent Posts

See All
bottom of page